As of June 1st 2021, the Characterisation Of caRdiac Disease in adolescents with perinatally-acquired HIV infection in the antiretroviral therapy era (CORD study) begins. This study is being led by EDCTP Career Development Fellow, Dr Edith Majonga and will last for 30 months. The main goal of the study is to investigate cardiac structural and functional disease, and underlying pathophysiology among adolescents aged 10-19 years, with perinatal HIV using cardiac magnetic resonance imaging and panel of cardiac, fibrosis and inflammatory biomarkers. Findings will give insight on the pathophysiological process of HIV-associated myocardial disease and inform interventional strategies to improve long-term health of adolescents with HIV.
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